Angeliki P Kourounakis Selected Research

EP2306

12/2007	EP2306 [2-(4-biphenyl)-4-methyl-octahydro-1,4-benzoxazin-2-ol, hydrobromide], a novel squalene synthase inhibitor, reduces atherosclerosis in the cholesterol-fed rabbit.
3/2006	Pharmacological characterization in vitro of EP2306 and EP2302, potent inhibitors of squalene synthase and lipid biosynthesis.

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Angeliki P Kourounakis Research Topics

Disease

9	Atherosclerosis 01/2019 - 03/2006
3	Edema (Dropsy) 04/2013 - 06/2002
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2007 - 07/2004
2	Inflammation (Inflammations) 06/2003 - 06/2002
1	Cardiovascular Diseases (Cardiovascular Disease) 09/2020
1	Hyperlipidemias (Hyperlipidemia) 11/2015
1	Muscular Diseases (Myopathy) 02/2015
1	Dyslipidemias (Dyslipidemia) 03/2014
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2013
1	Type 2 Diabetes Mellitus (MODY) 04/2013
1	Coronary Artery Disease (Coronary Atherosclerosis) 12/2007
1	Brain Ischemia (Cerebral Ischemia) 01/2007

Drug/Important Bio-Agent (IBA)

7	AntioxidantsIBA 01/2019 - 01/2007
4	Pharmaceutical PreparationsIBA 09/2020 - 06/2008
4	Farnesyl-Diphosphate Farnesyltransferase (Squalene Synthase)IBA 09/2017 - 12/2007
3	morpholineIBA 09/2017 - 11/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 02/2015
2	CholesterolIBA 06/2008 - 12/2007
2	EP2302IBA 06/2008 - 03/2006
2	LipidsIBA 12/2007 - 03/2006
2	EP2306IBA 12/2007 - 03/2006
2	Free RadicalsIBA 06/2003 - 06/2002
1	Hypolipidemic Agents (Antihyperlipidemics)IBA 01/2019
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2019
1	1,4-benzothiazineIBA 01/2017
1	oxidized low density lipoproteinIBA 11/2015
1	Hypoglycemic Agents (Hypoglycemics)IBA 04/2013
1	diphenyl (biphenyl)IBA 12/2007
1	Glutathione (Reduced Glutathione)IBA 01/2007
1	Ibuprofen (Motrin)FDA LinkGeneric 01/2007
1	Proline (L-Proline)FDA Link 01/2007
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 07/2004
1	Indomethacin (Indometacin)FDA LinkGeneric 06/2003
1	Lipoxygenase (Lipoxygenase-1)IBA 06/2003
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 06/2002
1	alkanninIBA 06/2002
1	Hydroxyl RadicalIBA 06/2002
1	shikoninIBA 06/2002